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Pyr10, MedChemExpress

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Quantity:
5 mg
10 mg
50 mg
Unit Size:
10mg
50mg
5mg
Description
Pyr10 is a pyrazole derivative and a selective TRP cation 3 (TRPC3) inhibitor. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with an IC50 of 0.72 ÎĽM (IC50 of 13.08 ÎĽM for store operated Ca2+ entry in BRL-2H3 cells). Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels.
Specifications
Specifications
Chemical Name or Material | Pyr10 |
CAS | 1315323-00-2 |
Color | Off-White |
Purity Grade Notes | Research |
Molecular Formula | C18H13F6N3O2S |
Quantity | 5 mg |
Solubility Information | DMSO : 100 mg/mL (222.53 mM; Need ultrasonic) |
SMILES | O=S(C1=CC=C(C)C=C1)(NC2=CC=C(N3N=C(C(F)(F)F)C=C3C(F)(F)F)C=C2)=O |
Molecular Weight (g/mol) | 449.37 |
Formula Weight | 449.37 |
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Research purposes only
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Pyr10, MedChemExpress
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