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Tocris Bioscience™ PX 12
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Artikelnummer. 18015872
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50 mg
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18015872 10 mg
18044942 50 mg
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Artikelnummer. 18015872 Leverandør Tocris Bioscience™ Leverandørnr. 2954/10

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Beskrivelse

Thioredoxin-1 inhibitor

Thioredoxin-1 (Trx-1) inhibitor; irreversibly inactivates Trx-1 as a substrate for reduction by thioredoxin reductase (TR); competitively inhibits the reduction of Trx-1 by TR (Ki = 30.8 μM). Attenuates expression of HIF-1α, VEGF and iNOS (IC50 values are 7.2, 10.4 and 18.1 μM respectively). Exhibits antitumor activity; directly inhibits tubulin in vitro and decreases tumor microvessel density in vivo.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 141400-58-0
Molekylær formel C7H12N2S2

Tekniske data

Kemisk navn eller materiale PX 12
Mængde 10 mg
Formel vægt 188.31
Renhed >99%
Molekylvægt (g/mol) 188.31
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