missing translation for 'onlineSavingsMsg'
Learn More

Puromycin, 10 mg/mL in distilled water, sterile-filtered, Alfa Aesar™

Used as a substrate of Mdr-1. It is been widely used in cell culture applications.

Brand:  Alfa Aesar J67236.8=

Additional Details : Weight : 0.01000kg

Quantity 5 x 1mL

 View more versions of this product

Product Code. 15480717

  • 1812.28 DKK / Each


Estimated Shipment
19-10-2020
Add to basket

Description

Description

Applications
Puromycin is also used as a substrate of Mdr-1. It is been widely used in cell culture applications. It also induces apoptosis which was found as parallel apoptosis caused by deprivation of neuronal growth factor (NGF) in developing chick sympathetic neurons; however, this apoptotic activity can be inhibited by several transcriptional inhibitors such as: actinomycin D and α-amanitin (sc-202440) which has lead researchers to hypothesize that apoptosis is triggered through the transcription of particular genes. Shown to arrest cells in G2/M phase. Puromycin is an inhibitor of CD13 and DPP7.

Solubility
Soluble in water (50 mg/ml at 20°C).

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use. Optimal working concentration of puromycin varies between cell lines. Usually, the working concentration for eukaryote cell culture is 1-10 µg/ml
Specifications

Chemical Identifiers

53-79-2
471.518
RXWNCPJZOCPEPQ-NVWDDTSBSA-N
CHEBI:17939
CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O
C22H29N7O5
MFCD00012691
439530
(2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide

Specifications

Puromycin
53-79-2
MFCD00012691
RXWNCPJZOCPEPQ-NVWDDTSBSA-N
(2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide
439530
Liquid
5 x 1mL
sterile-filtered
C22H29N7O5
Soluble in water (50mg/ml at 20°C).
CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O
471.518
CHEBI:17939
10mg/mL in distilled water
Videos
SDS Documents