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PROK2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA5110221
Additional Details : Weight : 0.01000kg
Description
Immunogen sequence: LTPRAGDAAV ITGACDKDSQ CGGGMCCAVS IWVKSIRICT PMGKLGDSCH PLTRKNNFGN GRQERRKRKR SKRKKEVPFF GRRMHHTCPC LPGLACLRTS FNRFICLAQK
Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.Specifications
| PROK2 | |
| Polyclonal | |
| Unconjugated | |
| PROK2 | |
| Bombina variegata 8 kD protein; Bombina variegata 8kDa protein; Bv 8 homolog (Bombina variegata); BV8; Bv8/prokineticin 2-like protein; Bv8/prokineticin 2-like protein splice variant; HH4; homolog of mouse Bv8 (Bombina variegata 8 kDa); homolog of mouse Bv8 (Bombina variegata 8 kDa); prokineticin 2; KAL4; MIT1; PK2; Prok1; Prok2; prokineticin 1; prokineticin 2; prokineticin 2 beta; prokineticin-2; Protein Bv8 homolog; secreted protein | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 192206, 50501, 60675 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 2.73 mg/mL | |
| PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
| Q8R413, Q9HC23, Q9QXU7 | |
| PROK2 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 20-129 of human PROK2 (NP_001119600.1). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |