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PRN694, MedChemExpress

Artikelnummer. 16445288
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16441279 1 mg 1mg
16413326 25 mg -
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Artikelnummer. 16445288 Leverandør Medchem Express Leverandørnr. HY12680

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Beskrivelse

MedChemExpress PRN694 is an irreversible, highly selective and potent covalent interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) dual inhibitor with IC50s of 0.3 nM and 1.4 nM, respectively. PRN694 exhibits extended target residence time on ITK and RLK, enabling durable attenuation of effector cells in vitro and in vivo.

PRN694 is an irreversible, highly selective and potent covalent interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) dual inhibitor with IC50s of 0.3 nM and 1.4 nM, respectively. PRN694 exhibits extended target residence time on ITK and RLK, enabling durable attenuation of effector cells in vitro and in vivo.

Tekniske data

Kemisk navn eller materiale PRN694
CAS 1575818-46-0
Farve Light Brown
Renhedsgrad noter Research
Molekylær formel C28H35F2N5O2S
Mængde 10 mg
Opløselighedsinformation DMSO : 125 mg/mL (229.92 mM; Need ultrasonic and warming)
SMIL O=C(C1=CC=C(C(F)F)S1)NC2=NC3=CC(CN[C@@H](C)C(C)(C)C)=CC=C3N2C[C@@H]4N(C(C=C)=O)CCC4
Molekylvægt (g/mol) 543.67
Formel vægt 543.67
Procent renhed 99.0%
Grad Research
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Til brug med (applikation) COVID-19-immunoregulation
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Research purposes only

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