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PQ401, MedChemExpress

Artikelnummer. 16465808
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Mængde:
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50 mg
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Artikelnummer. Mængde
16465808 10 mg
16401967 50 mg
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Artikelnummer. 16465808 Leverandør Medchem Express Leverandørnr. HY13686

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Beskrivelse

MedChemExpress PQ401 is a potent inhibitor of IGF-IR signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC50 of 12.0 μM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC50, 6 μM). PQ401 is a potential agent for breast and other IGF-I-sensitive cancers. PQ401 induces caspase-mediated apoptosis.

PQ401 is a potent inhibitor of IGF-IR signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC50 of 12.0 μM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC50, 6 μM). PQ401 is a potential agent for breast and other IGF-I-sensitive cancers. PQ401 induces caspase-mediated apoptosis.

Tekniske data

Kemisk navn eller materiale PQ401
CAS 196868-63-0
Farve White
Renhedsgrad noter Research
Molekylær formel C18H16ClN3O2
Mængde 10 mg
Opløselighedsinformation DMSO : 14.29 mg/mL (41.81 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMIL O=C(NC1=CC(C)=NC2=CC=CC=C12)NC3=C(OC)C=CC(Cl)=C3
Molekylvægt (g/mol) 341.79
Formel vægt 341.79
Procent renhed 99.88%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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