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PP 121
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Artikelnummer. 18755856
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Mængde:
5 mg
25 mg
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Artikelnummer. Mængde
18755856 25 mg
18749206 5 mg
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Artikelnummer. 18755856 Leverandør Tocris Bioscience Leverandørnr. 3894/25

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Beskrivelse

Dual kinase inhibitor; inhibits PI 3-K family kinases

PP 121 is a dual inhibitor of receptor tyrosine kinases (RTKs) (IC50 < 0.02 μM for Abl, Src, VEGFR-2 and PDGFR) and PI 3-K family kinases (IC50 < 0.06 μM for p110α, DNA-PK and mTOR). Exhibits no significant effect on receptor serine/threonine kinases (RSTKs). Blocks the proliferation of tumor cells by direct inhibition of PI 3-K, mTOR, Src and the VEGF receptor.
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale 1-Cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 1092788-83-4
Analyseprocentområde >99%
Mængde 25 mg
Molekylær formel C17H17N7
Formel vægt Observed MW: 319.36
Produkttitel
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