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Invitrogen™ Human PIP5K1C, GST Tag Recombinant Protein

Artikelnummer. 15950423
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Mængde:
1 mg
100 μg
20 μg
Pakningsstørrelse:
1mg
20µg
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Artikelnummer. 15950423

Brand: Invitrogen™ A33522

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Beskrivelse

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This PIP5K1C recombinant human protein (full length) was expressed in insect cells. PIP5K1C recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Adapta™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Full Length, Recombinant, Active The gene accession number for PIP5K1C is NP_036530.1.

PIP5K1C lipid kinase or phosphatidylinositol-4-phosphate 5-kinase 1 gamma phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP5K1C is found at synapses and has been found to play roles in endocytosis and cell migration. PIP5K1C directly associates with -beta-catenin and increases -beta-catenin activity downstream of growth factor stimulation. PIP5K1C expression and kinase activity enhance -beta-catenin phosphorylation on residues that promote nuclear importation and transcriptional activity. PIP5K1C deficiency impairs neutrophil recruitment as a result of defect in adhesion. PIP5K1C regulated the adhesion through facilitation of RhoA GTPase and integrin activation by chemo attractants.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer O60331
Koncentration See Label
Til brug med (applikation) Kinase Assay
Formulering 50mM tris HCl with 25% glycerol, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 150mM NaCl, 0.1mM PMSF and no preservative; pH 7.5
Gen-id (Entrez) 23396
Molekylvægt (g/mol) 99.6 kDa
Navn Human PIP5K1C, GST Tag
pH-område 7.5
Oprensningsmetode Purified
Mængde 20 μg
Opbevaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias AI115456; AI835305; diphosphoinositide kinase; Kiaa0589; LCCS3; phosphatidylinositol 4-phosphate 5-kinase type I gamma; Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma; phosphatidylinositol-4-phosphate 5-kinase type I gamma; phosphatidylinositol-4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma; Pip5k1c; PIP5K1-gamma; PIP5Kgamma; PIP5K-GAMMA; PIP5KI gamma; Pip5kIgamma; PIP5KI-gamma; PIPKIg_v4; ptdIns(4)P-5-kinase 1 gamma; ptdIns(4)P-5-kinase gamma; ptdInsPKIgamma; type I PIP kinase
Fælles navn PIP5K1C
Gen symbol PIP5K1C
KinaseFamily PI3 Kinase
Produkttype Protein
Konjugeret Unconjugated
Arter Human
Rekombinant Recombinant
Protein tag GST-tag
Sekvens Full length
Indhold og opbevaring -80°C, Avoid Freeze/Thaw Cycles
Forsendelsestilstand Dry Ice
Udtrykssystem Insect cells
Protein familie Kinases & Inhibitors
Protein form Full Length, Recombinant, Active
Form Liquid
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