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Invitrogen™ Human PIK3CB/PIK3R2 (p110 beta/p85 beta), His Tag Recombinant Protein
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Mængde:
1 mg
100 μg
20 μg
Pakningsstørrelse:
1mg
20µg
Beskrivelse
PIK3CB/PIK3R2 lipid kinase (p110 beta/p85 beta) or Phosphatidylinositol 3-kinase (PI3K) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids which functions in signaling pathways that regulate cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kDa catalytic subunit and a 85-kDa adaptor subunit. PIK3CB plays a critical role in regulating the formation and stability of alpha-2B-beta-3 integrin adhesion bonds, which are necessary for shear force-induced platelet activation. PIK3CB sustains alpha-2B-beta-3 integrin activation and stabilized platelet aggregation by regulating both integrin-dependent calcium flux and Gi activation of RAP1B.

Tekniske data
Tekniske data
Adgangsnummer | O00459, P42338 |
Koncentration | See Label |
Til brug med (applikation) | Kinase Assay |
Formulering | 50 mM sodium phosphate with 0.1 mM PMSF, 0.25 mM DTT, 150 mM Imidazole, 25% glycerol, 300 mM NaCl and no preservative; pH 7 |
Gen-id (Entrez) | 5291, 5296 |
Molekylvægt (g/mol) | 123.7-83.5 kDa |
Navn | Human PIK3CB/PIK3R2 (p110 beta/p85 beta), His Tag |
Mængde | 100 μg |
Gene Alias | PIK3CB; PIK3R2 |
Fælles navn | PIK3CB/PIK3R2 |
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Certifikater
Certifikater
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1 resultater fundet
Partinummer | Certifikattype | Dato | Artikelnummer |
---|---|---|---|
2354477 | Analysecertifikat | 08/04/2021 | A32910 |
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Produkttitel
Invitrogen™ Human PIK3CB/PIK3R2 (p110 beta/p85 beta), His Tag Recombinant Protein >
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