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Invitrogen™ Human PIK3C3 (hVPS34), GST Tag Recombinant Protein

Artikelnummer. 10073324
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Mængde:
100 μg
20 μg
Pakningsstørrelse:
100µg
Hver
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Artikelnummer. 10073324

Brand: Invitrogen™ PV5126

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Beskrivelse

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. PIK3C3 phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes. PIK3C3 is involved in coupling nutrient signaling to mTOR and also plays a role in autophagy and intracellular trafficking. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer Q8NEB9
Koncentration See Label
Til brug med (applikation) Kinase Assay
Formulering 50mM tris with 0.5mM EDTA, 150mM NaCl, 50% glycerol, 2mM DTT, 0.02% CHAPS and no preservative; pH 7.5
Gen-id (Entrez) 5289
Molekylvægt (g/mol) 129 kDa
Navn Human PIK3C3 (hVPS34), GST Tag
pH-område 7.5
Oprensningsmetode Purified
Mængde 20 μg
Opbevaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias 5330434F23Rik; catalytic phosphatidylinositol 3-kinase 3; catalytic subunit type 3 Antibody; class 3 phosphoinositide-3-kinase; Class III PI 3-kinase; hVps34; hVps34 Antibody; OTTMUSP00000023341; OTTMUSP00000023350; phosphatidylinositol 3-kinase; Phosphatidylinositol 3-kinase catalytic subunit type 3; phosphatidylinositol 3-kinase p100 subunit; phosphatidylinositol 3-kinase, catalytic subunit type 3; Phosphoinositide-3-kinase class 3; phosphoinositide-3-kinase, class 3; PI3K type 3; PI-3K Vps34p; pi3kc3; PI3-kinase type 3; Pik3c3; PIK3C3 Antibody; PtdIns-3-kinase type 3; VPS34
Fælles navn VPS34
Gen symbol Pik3c3
KinaseFamily PI3 Kinase Family
Produkttype Protein
Konjugeret Unconjugated
Arter Human
Rekombinant Recombinant
Protein tag GST-tag
Sekvens Full length
Indhold og opbevaring -80°C, Avoid Freeze/Thaw Cycles
Assay Entry Biochemical ADP accumulation
Kinase Group Lipid Kinases
Forsendelsestilstand Dry Ice
Systemkompatibilitet Adapta™
Målindgang PIK3C3
Target Gene phosphoinositide-3-kinase, class 3
Udtrykssystem Baculovirus
Protein familie Kinases & Inhibitors
Protein form Recombinant, Full Length
Form Liquid
Protein undertype Lipid Kinases
Forskningskategori Signal Transduction
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