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Thermo Scientific™ CHAPS Detergent (3-((3-cholamidopropyl) dimethylammonio)-1-propanesulfonate)

Non-denaturing Zwitterionic detergents that disrupt nonspecific protein interactions with less protein aggregation than nonionic detergents.

Brand:  Thermo Scientific™ 28300

Additional Details : Weight : 0.80000kg

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Product Code. 11851445

  • 1248.00 DKK / 5g


In stock, ready to ship: 12
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Description

Description

Thermo Scientific™ CHAPS is a zwitterionic detergent that is especially well suited for protecting the native state of proteins.

CHAPS is a sulfobetaine derivatives of cholic acid. This zwitterionic detergent is useful for membrane protein solubilization when it is important to maintain protein activity. CHAPS detergent is soluble over a wide range of pH (2 to 12) and are easily removed from solution by dialysis because of their high critical micelle concentration (CMC).

Highlights:

  • Versatile zwitterionic detergents
  • Provide mild but effective lysis of cultured mammalian cells
  • Nondenaturing and generally do not inactivate protein functions
  • Can be removed from solution by dialysis
  • Commonly used for isoelectric focusing (IEF) and 2D electrophoresis

Properties of CHAPS detergent:

  • Chemical Name: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
  • Molecular Weight: 614.88
  • Detergent Class: Zwitterionic
  • Aggregation Number: 10
  • Micelle Molecular Weight: 6149
  • Critical Micelle Concentration (CMC): 8 to 10mM (0.4920 to 0.6150%, w/v)
  • Cloud Point: ≥ 100°C
  • Dialyzable: Yes

 

Specifications

Specifications

Powder
Detergent (Pure)
CHAPS
5g
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