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PI 3065, >98%, Tocris Bioscience™

Artikelnummer. 30000961
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50 mg
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30000961 10 mg
30000890 50 mg
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Artikelnummer. 30000961 Leverandør Tocris Bioscience Leverandørnr. 5919/10

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Beskrivelse

Potent and selective PI 3-kinase p110δ inhibitor

Potent and selective PI 3-kinase p110δ inhibitor (IC50 = 5 nM; Ki = 1.5 nM). Exhibits >100-fold selectivity over p100α, p100γ and p100β isoforms (IC50 values are 600, 910, >10,000 nM, respectively). Attenuates 4TI tumor growth and metastasis in vivo.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 955977-50-1
Molekylær formel C27H31FN6OS
Molekylvægt (g/mol) 506.64
MDL nummer MFCD28167771
InChI nøgle YDNOHCOYQVZOMC-UHFFFAOYSA-N
Synonym 4-6-4-cyclopropylmethyl piperazin-1-yl methyl-2-5-fluoro-1h-indol-4-yl thieno 3,2-d pyrimidin-4-yl morpholine, d01ssi, 4-6-4-cyclopropylmethyl piperazin-1-yl methyl-2-5-fluoro-1h-indol-4-yl thieno 3,2, 6-4-cyclopropylmethyl-piperazin-1-ylmethyl-2-5-fluoro-1h-indol-4-yl-4-morpholin-4-yl-thieno 3,2-d pyrimidine, 6-4-cyclopropylmethyl-1-piperazinyl methyl-2-5-fluoro-1h-indol-4-yl-4-4-morpholinyl-thieno 3,2-d pyrimidine
PubChem CID 24937012
IUPAC navn 4-(6-{[4-(cyclopropylmethyl)piperazin-1-yl]methyl}-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl)-5-fluoro-1H-indole
SMIL FC1=CC=C2NC=CC2=C1C1=NC(N2CCOCC2)=C2SC(CN3CCN(CC4CC4)CC3)=CC2=N1

Tekniske data

Kemisk navn eller materiale 6-[[4-(Cyclopropylmethyl)-1-piperazinyl]methyl]-2-(5-fluoro-1H-indol-4-yl)-4-(4-morpholinyl)-thieno[
Renhedsgrad noter >98%
Lineær formel C27H31FN6OS
Mængde 10 mg
Opløselighedsinformation Soluble to 20mM in DMSO
Formel vægt 506.64
Produkttitel
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