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Invitrogen™ Phospho-NFkB p65 (Ser468) Polyclonal Antibody
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Artikelnummer. 17732674
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100 μL
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17732674 100 μL
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Artikelnummer. 17732674 Leverandør Invitrogen™ Leverandørnr. PA5121275

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Beskrivelse

Rabbit Polyclonal Antibody

Positive test controls include: NIH/3T3. The target is usually found in the following locations: Cytoplasm, Nucleus. Immunogen sequence: VDNSE.

Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB P65 is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A) and belongs to the Rel family of proteins. It is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. It specifically plays a key role in transcription of immunoglobulin k (kappa) gene in mature B-lymphoid cells.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Phospho-NFkB p65 (Ser468)
Applikationer ELISA, Western Blot
Klassifikation Polyclonal
Koncentration 1.06 mg/mL
Konjugeret Unconjugated
Formulering PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene RELA
Genadgangsnr. Q04206
Gene Alias avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela
Gensymboler RELA
Værtsarter Rabbit
Immunogen A synthetic phosphorylated peptide around S468 of human Phospho-NF-kB p65/RelA-S468 (NP_0011386101).
Oprensningsmetode Affinity Chromatography
Mængde 100 μL
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 309165, 5970
Målarter Human, Rat
Indhold og opbevaring -20°C, Avoid Freeze/Thaw Cycles
Produkttype Antibody
Form Liquid
Isotype IgG
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