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Phospho-IP3 Receptor 1 (Tyr353) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5106062

Produktkode 16624595


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Beskrivelse

Beskrivelse

Antibody detects endogenous levels of IP3 Receptor only when phosphorylated at Tyr353.

Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.
TRUSTED_SUSTAINABILITY
Tekniske data

Tekniske data

Phospho-IP3 Receptor 1 (Tyr353)
Polyclonal
Unconjugated
Itpr1
ACV; CLA4; D6Pas2; ENSMUSG00000072853; Gm10429; I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 1,4,5-trisphosphate receptor, type 1; inositol 1,4,5-trisphosphate-binding protein P400; InsP>3<R type I; Insp3r; InsP3R type I; insP3R1; IP3 receptor; IP3 receptor isoform 1; Ip3r; IP-3-R; IP3R 1; IP3R1; Itpr1; Itpr-1; opisthotonus; opt; P400; Pcd6; Pcp1; Pcp-1; PPP1R94; protein PCD-6; protein phosphatase 1, regulatory subunit 94; Purkinje cell protein 1; SCA15; SCA16; SCA29; SI-SIII-SIIA; Type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor
Rabbit
sequential chromatography
RUO
16438, 25262, 3708
-20°C
Liquid
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P11881, P29994, Q14643
Itpr1
A synthesized peptide derived from human ITPR1(Accession Q14643), corresponding to amino acid residues around phosphorylated Tyr353.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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