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Invitrogen™ Phospho-4EBP1 (Thr37, Thr46) Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA577963

Produktkode 16336674

  • 4365.00 DKK / 100µL

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Beskrivelse

Beskrivelse

Positive Control: Neuro2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2, HeLa, 293T (starvation for 24 hr), 293T (starvation for 24 hr and 20%FBS treatment for 0.5 hr) Predicted Reactivity: Zebrafish (100%), Pig (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
TRUSTED_SUSTAINABILITY
Tekniske data

Tekniske data

Phospho-4EBP1 (Thr37, Thr46)
Polyclonal
Unconjugated
EIF4EBP1
4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Rabbit
Antigen affinity chromatography
RUO
116636, 13685, 1978
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
0.12 mg/mL
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Q13541, Q60876, Q62622
EIF4EBP1
Carrier-protein conjugated synthetic peptide surrounding phospho Thr37/Thr46 of human 4E-BP1. The exact sequence is proprietary.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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