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Phenoxodiol, MedChemExpress

Artikelnummer. 16495818
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16495818 10 mg
16478487 5 mg
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Artikelnummer. 16495818 Leverandør Medchem Express Leverandørnr. HY13721

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Beskrivelse

MedChemExpress Phenoxodiol, a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner.

Phenoxodiol, a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner.

Tekniske data

Kemisk navn eller materiale Phenoxodiol
CAS 81267-65-4
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C15H12O3
Mængde 10 mg
Synonym Idronoxil Dehydroequol Haginin E
Opløselighedsinformation DMSO : ≥ 100 mg/mL (416.23 mM) ∣H2O : 1 mg/mL (4.16 mM; Need ultrasonic)
SMIL OC1=CC=C2C=C(C3=CC=C(O)C=C3)COC2=C1
Molekylvægt (g/mol) 240.25
Formel vægt 240.25
Procent renhed 95.0%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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