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Tocris Bioscience™ PFI 3

Potent and selective SMARCA2/4 and polybromo 1 inhibitor
Brand: Tocris Bioscience™ 5072/10
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Description
PFI 3 is a potent and selective polybromo 1 (PBRM1) and SMARCA4 inhibitor (Kd values are 48 and 89 nM respectively) that also inhibits SMARCA2. This compoud displays 30-fold selectivity over other sub-family branches. PFI 3 accelerates FRAP recovery in cells at a concentration of 1 ÎĽM.
Specifications
(2E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]prop-2-en-1-one | |
10 mg | |
321.37 |
1819363-80-8 | |
C19H19N3O2 | |
98% |
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Product Title
Tocris Bioscience™ PFI 3 > 10 mg
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