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PF-CBP1 hydrochloride, MedChemExpress

Artikelnummer. 16488008
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Artikelnummer. 16488008 Leverandør Medchem Express Leverandørnr. HY19999A

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MedChemExpress PF-CBP1 hydrochloride is a highly selective inhibitor of the CREB binding protein bromodomain (CBP BRD).

PF-CBP1 inhibits CREBBP and EP300 bromodomains with IC50 of 125 nM and 363 nM respectively. PF-CBP1 hydrochloride reduces LPS-induced inflammatory cytokines expression (IL-1β, IL-6 and IFN-β) in primary macrophages. PF-CBP1 hydrochloride also downregulates RGS4 expression cortical neurons and can be used for the research of neurological disorders, including epilepsy and parkinson's disease, et al.

Tekniske data

Kemisk navn eller materiale PF-CBP1 hydrochloride
CAS 2070014-93-4
Farve White
Renhedsgrad noter Research
Molekylær formel C29H37ClN4O3
Mængde 10 mg
Opløselighedsinformation DMSO : 100 mg/mL (190.45 mM; Need ultrasonic) ∣H2O : 1 mg/mL (1.90 mM; Need ultrasonic)
SMIL CCCOC1=CC=C(CCC2=NC3=CC(C4=C(C)ON=C4C)=CC=C3N2CCN5CCOCC5)C=C1.Cl[H]
Molekylvægt (g/mol) 525.08
Formel vægt 525.08
Procent renhed 95.95%
Grad Research
Fysisk form Powder
Til brug med (applikation) Neuroscience-Neurodegeneration
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Research purposes only

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