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PF-CBP1 hydrochloride, MedChemExpress
Beskrivelse
PF-CBP1 inhibits CREBBP and EP300 bromodomains with IC50 of 125 nM and 363 nM respectively. PF-CBP1 hydrochloride reduces LPS-induced inflammatory cytokines expression (IL-1β, IL-6 and IFN-β) in primary macrophages. PF-CBP1 hydrochloride also downregulates RGS4 expression cortical neurons and can be used for the research of neurological disorders, including epilepsy and parkinson's disease, et al.
Tekniske data
Tekniske data
| Kemisk navn eller materiale | PF-CBP1 hydrochloride |
| CAS | 2070014-93-4 |
| Farve | White |
| Renhedsgrad noter | Research |
| Molekylær formel | C29H37ClN4O3 |
| Mængde | 10 mg |
| Opløselighedsinformation | DMSO : 100 mg/mL (190.45 mM; Need ultrasonic) ∣H2O : 1 mg/mL (1.90 mM; Need ultrasonic) |
| SMIL | CCCOC1=CC=C(CCC2=NC3=CC(C4=C(C)ON=C4C)=CC=C3N2CCN5CCOCC5)C=C1.Cl[H] |
| Molekylvægt (g/mol) | 525.08 |
| Formel vægt | 525.08 |
| Show More |
Research purposes only
Product Title
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