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Tocris Bioscience™ PF 06281355, >98%
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Artikelnummer. 30000984
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50 mg
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30000984 50 mg
30000902 10 mg
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Artikelnummer. 30000984 Leverandør Tocris Bioscience™ Leverandørnr. 6004/50

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Beskrivelse

Selective myeloperoxidase (MPO) inhibitor

Selective myeloperoxidase (MPO) inhibitor (IC50 = 1.5 μM in LPS-stimulated human whole blood). Selective for MPO over a panel of 50 receptors, enzymes, ion channels and transporters, including thyroid peroxidase. Inhibits MPO activity in peritoneal lavage and plasma in a murine peritonitis model. Also reduces lung edema in a murine pulmonary immune complex vasculitis model. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 1435467-38-1
Molekylær formel C14H15N3O4S

Tekniske data

Kemisk navn eller materiale 6-(2,5-Dimethoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo-1(2H)-pyrimidineacetamide
Mængde 50 mg
Opløselighed Soluble to 20mM in DMSO with gentle warming
Formel vægt 321.35
Renhed >98%
Molekylvægt (g/mol) 321.351
Produkttitel
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