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Tocris Bioscience™ PF 06273340
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Artikelnummer. 18718219
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Mængde:
10 mg
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Artikelnummer. Mængde
18718219 10 mg
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Artikelnummer. 18718219 Leverandør Tocris Bioscience™ Leverandørnr. 6115/10

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Potent and selective pan-Trk inhibitor; peripherally restricted

PF 06273340 is a potent and selective pan-Trk inhibitor (IC50 values are 1, 2 and 6 nM for Trk C, B and A, respectively). Selective for Trk over a panel of ion channels, receptors and other enzymes. Peripherally restricted. Exhibits efficacy in a rodent model of inflammatory pain. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale PF 06273340
CAS 1402438-74-7
Synonym N-[5-[[2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-2-pyridineacetamide
Mængde 10 mg
Opløselighed Soluble to 100mM in DMSO
Molekylær formel C23H22ClN7O3
Formel vægt 479.93
Fysisk form Solid
Farve Orange
Produkttype Bioactive Small Molecule
Renhed >98%
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For Research Use Only.

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