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Pexidartinib hydrochloride, MedChemExpress

Artikelnummer. 16483197
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5 mg
10 mg
50 mg
Pakningsstørrelse:
10mg
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16483197 50 mg -
16449707 5 mg -
16447178 10 mg 10mg
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Artikelnummer. 16483197 Leverandør Medchem Express Leverandørnr. HY16749A

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Beskrivelse

MedChemExpress Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity.

Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity.

Tekniske data

Kemisk navn eller materiale Pexidartinib hydrochloride
CAS 2040295-03-0
Farve White
Renhedsgrad noter Research
Molekylær formel C20H16Cl2F3N5
Mængde 50 mg
Synonym PLX-3397 hydrochloride
Opløselighedsinformation DMSO : 60 mg/mL (132.08 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic) (insoluble)
SMIL FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F.Cl
Molekylvægt (g/mol) 454.28
Formel vægt 454.28
Procent renhed 99.67%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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