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Peretinoin, MedChemExpress Product Code.: 16464196
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Peretinoin, MedChemExpress

Product Code. 16464196
100 mg, 100mg
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Product Code. 16464196

Brand: Medchem Express HY100008

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Description

MedChemExpress Peretinoin is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as retinoid X receptor (RXR) and retinoic acid receptor (RAR).

Peretinoin reduces the mRNA level of sphingosine kinase 1 (SPHK1) in vitro by downregulating a transcription factor, Sp1. Peretinoin prevents the progression of non-alcoholic steatohepatitis (NASH) and the development of hepatocellular carcinoma (HCC) through activating the autophagy pathway by increased Atg16L1 expression. Peretinoin inhibits HCV RNA amplification and virus release by altering lipid metabolism with a EC50 of 9 ÎĽM.

Specifications

Chemical Name or Material Peretinoin
CAS 81485-25-8
Color Yellow
Purity Grade Notes Research
Molecular Formula C20H30O2
Quantity 100 mg
Synonym NIK333
Solubility Information DMSO : 50 mg/mL (165.32 mM; Need ultrasonic)
SMILES C/C(C)=C/CC/C(C)=C/CC/C(C)=C/C=C/C(C)=C/C(O)=O
Molecular Weight (g/mol) 302.45
Formula Weight 302.45
Percent Purity 95.66%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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