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Invitrogen™ PDK4 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA513776

Produktkode 10382090

  • 4410.00 DKK / 200µL

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Beskrivelse

Beskrivelse

PDK4 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

PDK4 (PDHK4), along with the other PDHKs, regulates glucose metabolism by phosphorylating the E1 alpha subunit of the mitochondrial pyruvate dehydrogenase complex. Inhibition of PDHKs is viewed as a potential therapeutic treatment for type II diabetes. This protein is located in the matrix of the mitrochondria and it's expression is regulated by glucocorticoids, retinoic acid and insulin. PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
TRUSTED_SUSTAINABILITY
Tekniske data

Tekniske data

PDK4
Polyclonal
Unconjugated
Pdk4
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial; AV005916; kinase isozyme 4; lipoamide; PDHK4; Pdk4; pyruvate dehydrogenase; pyruvate dehydrogenase kinase 4; Pyruvate dehydrogenase kinase isoform 4; pyruvate dehydrogenase kinase, isoenzyme 4; pyruvate dehydrogenase kinase, isozyme 4; pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial; pyruvate dehydrogenate kinase 4
Rabbit
Antigen affinity chromatography, Protein A
RUO
27273, 5166
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
2 mg/mL
PBS with 0.09% sodium azide; pH 7.4
O70571, Q16654
Pdk4
KLH conjugated synthetic peptide between 382-410 amino acids from the C-terminal region of human PDK4.
200 μL
Primary
Human, Mouse
Antibody
IgG
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