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Paritaprevir, MedChemExpress

Artikelnummer. 16491467
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16491467 50 mg 50mg
16485258 10 mg 10mg
16447977 5 mg -
16435926 100 mg -
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Artikelnummer. 16491467 Leverandør Medchem Express Leverandørnr. HY12594

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Beskrivelse

MedChemExpress Paritaprevir (ABT-450) is a potent, orally active and antiviral non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. Paritaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.31 μM. Paritaprevir is metabolized primarily by cytochrome P450 (CYP) 3A. The plasma concentration and half-life of Paritaprevir can be enhanced by Ritonavir (a CYP450 inhibitor).

Paritaprevir (ABT-450) is a potent, orally active and antiviral non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. Paritaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.31 μM. Paritaprevir is metabolized primarily by cytochrome P450 (CYP) 3A. The plasma concentration and half-life of Paritaprevir can be enhanced by Ritonavir (a CYP450 inhibitor).

Tekniske data

Kemisk navn eller materiale Paritaprevir
CAS 1216941-48-8
Farve White
Renhedsgrad noter Research
Molekylær formel C40H43N7O7S
Mængde 50 mg
Synonym ABT-450 Veruprevir
Opløselighedsinformation DMSO : ≥ 125 mg/mL (163.21 mM) ∣H2O : ≥ 0.1 mg/mL (0.13 mM)
SMIL O=C([C@]1(NC([C@@]2([H])N3C[C@H](OC4=C(C=CC=C5)C5=C6C(C=CC=C6)=N4)C2)=O)[C@H](/C=C\CCCCC[C@H](NC(C7=NC=C(C)N=C7)=O)C3=O)C1)NS(=O)(C8CC8)=O
Molekylvægt (g/mol) 765.88
Formel vægt 765.88
Procent renhed 98.0%
Grad Research
Fysisk form Solid
Til brug med (applikation) COVID-19-anti-virus
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Research purposes only

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