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Pamapimod, MedChemExpress Product Code.: 16433948
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Pamapimod, MedChemExpress

Product Code. p-200101690
10 mg, 10mg
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10 mg
25 mg
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Product Code. 16433948

Brand: Medchem Express HY10405

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Description

MedChemExpress Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38α and p38β, respectively. Pamapimod has no activity against p38δ or p38γ isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases treatment.

Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38α and p38β, respectively. Pamapimod has no activity against p38δ or p38γ isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases treatment.

Specifications

Chemical Name or Material Pamapimod
CAS 449811-01-2
Color Off-White
Purity Grade Notes Research
Molecular Formula C19H20F2N4O4
Quantity 10 mg
Synonym Ro4402257 R1503
Solubility Information DMSO : ≥ 34 mg/mL (83.67 mM)
SMILES O=C1C(OC2=CC=C(F)C=C2F)=CC3=CN=C(NC(CCO)CCO)N=C3N1C
Molecular Weight (g/mol) 406.38
Formula Weight 406.38
Percent Purity 99.92%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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