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Palbociclib, MedChemExpress

Artikelnummer. 16494017
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Artikelnummer. 16494017 Leverandør Medchem Express Leverandørnr. HY50767

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Beskrivelse

MedChemExpress Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Tekniske data

Kemisk navn eller materiale Palbociclib
CAS 571190-30-2
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C24H29N7O2
Mængde 50 mg
Synonym PD 0332991
Opløselighedsinformation DMSO : 25 mg/mL (55.86 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C) ∣0.1 M HCL : 25 mg/mL (55.86 mM; ultrasonic and adjust pH to 4 with 0.1 M HCL) ∣H2O : 0.1 mg/mL (0.22 mM; Need ultrasonic)
SMIL O=C1C(C(C)=O)=C(C2=CN=C(N=C2N1C3CCCC3)NC4=CC=C(N5CCNCC5)C=N4)C
Molekylvægt (g/mol) 447.53
Formel vægt 447.53
Procent renhed 95.0%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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