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Tocris Bioscience™ PA 8
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Artikelnummer. 18736496
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10 mg
50 mg
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18736496 10 mg
18777306 50 mg
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Artikelnummer. 18736496 Leverandør Tocris Bioscience™ Leverandørnr. 6657/10

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Description

PAC1 receptor antagonist

PA 8 is a PAC1 receptor antagonist. Inhibits PACAP-induced CREB phosphorylation in PAC1, but not VPAC1 or VPAC2, expressing cells. Also inhibits PACAP-induced increases in cAMP levels in vitro (IC50 = 2 nM) and PACAP-induced aversive responses and mechanical allodynia following intrathecal injection in vivo.
TRUSTED_SUSTAINABILITY

Specifications

Kemisk navn eller materiale 2-Amino-5,8-dihydro-5-[3-methoxy-4-(2-propen-1-yloxy)phenyl]pyrido[2,3-d]pyrimidine-4,7(3H,6H)-dione
CAS 878437-15-1
Mængde 10 mg
Molekylær formel C17H18N4O4
Formel vægt 342.35
Renhed 98%
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