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OTS964 hydrochloride, MedChemExpress

Artikelnummer. 16487907
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Artikelnummer. 16487907 Leverandør Medchem Express Leverandørnr. HY12467

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MedChemExpress OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC50 of 28 nM. OTS964 hydrochloride is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM.

OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC50 of 28 nM. OTS964 hydrochloride is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM.

Tekniske data

Kemisk navn eller materiale OTS964 hydrochloride
CAS 1338545-07-5
Farve White
Renhedsgrad noter Research
Molekylær formel C23H25ClN2O2S
Mængde 5 mg
Opløselighedsinformation DMSO : ≥ 83.33 mg/mL (194.26 mM) ∣H2O : 1.43 mg/mL (3.33 mM; Need ultrasonic)
SMIL OC1=CC(C)=C2C(C3=C(SC=C3)C(N2)=O)=C1C4=CC=C([C@@H](C)CN(C)C)C=C4.Cl
Molekylvægt (g/mol) 428.97
Formel vægt 428.97
Procent renhed 95.59%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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