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Osimertinib mesylate, MedChemExpress

Artikelnummer. 16491196
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16491196 200 mg
16486926 100 mg
16482887 50 mg
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16451786 500 mg
16419367 5 mg
16411559 1 g
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Artikelnummer. 16491196 Leverandør Medchem Express Leverandørnr. HY15772A

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Beskrivelse

MedChemExpress Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer.

Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer.

Tekniske data

Kemisk navn eller materiale Osimertinib mesylate
CAS 1421373-66-1
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C29H37N7O5S
Mængde 200 mg
Synonym AZD-9291 mesylate Mereletinib mesylate
Opløselighedsinformation DMSO : 13.89 mg/mL (23.32 mM; ultrasonic and warming and heat to 80°C)
SMIL C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O.CS(=O)(O)=O
Molekylvægt (g/mol) 595.71
Formel vægt 595.71
Procent renhed 98.74%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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