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Invitrogen™ Oncostatin M Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA576861
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Beskrivelse
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.
Tekniske data
| Oncostatin M | |
| Polyclonal | |
| Unconjugated | |
| OSM | |
| MGC20461; OncoM; oncostatin M; oncostatin-M; OSM | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 18413, 289747, 5008 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
| P13725, P53347, Q65Z15 | |
| OSM | |
| Recombinant full length Human Oncostatin M. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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