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Invitrogen™ Oncostatin M Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA547002
Denne vare kan ikke returneres.
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Beskrivelse
Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.
Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.
Tekniske data
| Oncostatin M | |
| Polyclonal | |
| Unconjugated | |
| OSM | |
| MGC20461; OncoM; oncostatin M; oncostatin-M; OSM | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 5008 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Flow Cytometry, Neutralization, Western Blot | |
| 0.2 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| P13725 | |
| OSM | |
| E. coli-derived recombinant human Oncostatin M/OSM Ala26-Arg221. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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Produkttitel
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