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Olodanrigan, MedChemExpress

Artikelnummer. 16498247
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Mængde:
5 mg
10 mg
25 mg
50 mg
Pakningsstørrelse:
10mg
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16425548 10 mg 10mg
16423356 25 mg -
16411717 50 mg -
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Artikelnummer. 16498247 Leverandør Medchem Express Leverandørnr. HY131065mg

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Beskrivelse

MedChemExpress Olodanrigan (EMA401) is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. It is under development as a neuropathic pain therapeutic agent. Olodanrigan (EMA401) analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons.

Olodanrigan (EMA401) is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. It is under development as a neuropathic pain therapeutic agent. Olodanrigan (EMA401) analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons.

Tekniske data

Kemisk navn eller materiale Olodanrigan
CAS 1316755-16-4
Farve White
Renhedsgrad noter Research
Molekylær formel C32H29NO5
Mængde 5 mg
Synonym EMA401 PD-126055
Opløselighedsinformation DMSO : ≥ 34 mg/mL (66.98 mM) ∣H2O : 0.1 mg/mL (0.20 mM; Need ultrasonic)
SMIL O=C([C@H]1N(C(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)CC4=C(C(OCC5=CC=CC=C5)=C(OC)C=C4)C1)O
Molekylvægt (g/mol) 507.58
Formel vægt 507.58
Procent renhed 99.16%
Grad Research
Fysisk form Solid
Til brug med (applikation) Neuroscience-Neuromodulation
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Research purposes only

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