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Tocris Bioscience™ Olaparib
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Artikelnummer. 18799536
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18799536 50 mg
18719856 10 mg
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To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”27950” to get your promotional price
Artikelnummer. 18799536 Leverandør Tocris Bioscience™ Leverandørnr. 7579/50
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    2980.00 DKK
    2817.15 DKK / 50mg
    Spare 162.85 DKK
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Forventet forsendelse: 11-09-2026
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1986.67 DKK valid until 2026-09-30
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Denne vare kan ikke returneres. Se returpolicy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”27950” to get your promotional price

Beskrivelse

Potent PARP inhibitor

Olaparib is a potent PARP2 and PARP1 inhibitor (IC50 values are 1 and 5 nM, respectively). Olaparib abolishes PARP-1 activity at a concentration of 30-100 nM in SW620 cell lysates. BRCA1-deficient cell lines are hypersensitive to PARP inhibition by Olaparib in comparison with BRCA1- and BRCA2-proficient cells. Olaparib potentiates the antitumor activity of the methylating chemotherapeutic agent Temozolomide (Cat. No. 2706) in xenograft mouse model. Olaparib is orally bioavailable in rats.
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale 4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2 H)-phthalazinone
CAS 763113-22-0
Mængde 50 mg
Mål Poly(ADP-ribose) Polymerase Inhibitors
Molekylær formel C24H23FN4O3
Renhed 0.98
Produkttitel
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