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Invitrogen™ Occludin Monoclonal Antibody (OC-3F10)
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Artikelnummer. 10017812
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Mængde:
100 μg
Pakningsstørrelse:
Hver
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10017812 100 μg Hver
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To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”27969” to get your promotional price
Artikelnummer. 10017812 Leverandør Invitrogen™ Leverandørnr. 331500

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2633.33 DKK valid until 2026-06-26
BEDSTE tilbudspris! Brug kampagnekoden "27969" for at få din tilbudspris.
Denne vare kan ikke returneres. Se returpolicy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”27969” to get your promotional price

Beskrivelse

Mouse Monoclonal Antibody

Occludin Monoclonal Antibody for ELISA, ICC/IF, Western Blot

Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa. Occludin is thought to be involved in regulating both the localization and the function of occludin. Polyunsaturated fatty acids are known to up-regulate occludin expression, increasing the transendothelial cell resistance and reducing the cellular permeability to large molecules. The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at cell-cell contact sites, whereas non-neural tissues show lower expression and discontinuous distribution. Overall structural features of the occludin protein are highly conserved in all the species examined. Under-expression of tight junction proteins, including occludin, is a key molecular abnormality responsible for the increased permeability of tumor endothelial tight junctions, which contributes to brain tumor edemas.
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Tekniske data

Antigen Occludin
Applikationer ELISA, Western Blot, Immunocytochemistry
Klassifikation Monoclonal
Klon OC-3F10
Koncentration 0.5 mg/mL
Konjugeret Unconjugated
Formulering PBS with 0.1% sodium azide; pH 7.4
Gene OCLN
Genadgangsnr. Q16625, Q28269, Q61146, Q6P6T5
Gene Alias AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein
Gensymboler OCLN
Værtsarter Mouse
Immunogen GST fusion protein consisting of the C-terminal region (~150aa) of human occludin.
Oprensningsmetode Protein A
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 100506658, 18260, 403844, 83497
Målarter Human, Mouse, Rat, Canine
Indhold og opbevaring -20°C
Produkttype Antibody
Form Liquid
Isotype IgG1 κ
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