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Invitrogen™ Human NTRK3 (TRKC), His Tag Recombinant Protein

Artikelnummer. 11513477
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Mængde:
1 mg
10 μg
Pakningsstørrelse:
10µg
1mg
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Artikelnummer. 11513477

Brand: Invitrogen™ PV3617

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Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Catalytic Domain, Cytoplasmic.

NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.
TRUSTED_SUSTAINABILITY

Specifications

Adgangsnummer Q16288
Koncentration See Label
Til brug med (applikation) Kinase Assay
Formulering 50mM tris HCl with 0.05% Triton X-100, 50% glycerol, 4mM DTT, 150mM NaCl, 0.5mM EDTA and no preservative; pH 7.5
Gen-id (Entrez) 4916
Molekylvægt (g/mol) 41.2 kDa
Navn Human NTRK3 (TRKC), His Tag
pH-område 7.5
Oprensningsmetode Purified
Mængde 10 μg
Opbevaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C
Fælles navn TrkC
Gen symbol Ntrk3
KinaseFamily Neurotrophic Receptor (NTRK) Kinase Family
Protein længde 510-825
Produkttype Protein
Konjugeret Unconjugated
Arter Human
Rekombinant Recombinant
Protein tag His-tag
Sekvens 510-825
Indhold og opbevaring -80°C, Avoid Freeze/Thaw Cycles
Assay Entry Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity
Kinase Group Tyrosine Kinases
Forsendelsestilstand Dry Ice
Systemkompatibilitet LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™
Målindgang NTRK3
Target Gene neurotrophic tyrosine kinase, receptor, type 3
Udtrykssystem Baculovirus
Protein familie Kinases & Inhibitors
Protein form Recombinant, Catalytic Domain, Cytoplasmic
Form Liquid
Protein undertype Receptor Tyrosine Kinases
Forskningskategori Signal Transduction
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