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Invitrogen™ NSE2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA565676
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Beskrivelse
Immunogen sequence: SQTNFTCPITK EEMKKPVKNK VCGHTYEEDA IVRMIESRQK RKKKAYCPQI GCSHTDIRKS DLIQDEALRR AIENHNKK Highest antigen sequence identity to the following orthologs - mouse 84%, rat 84%.
This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients.
Tekniske data
| NSE2 | |
| Polyclonal | |
| Unconjugated | |
| Nsmce2 | |
| 1110014D18Rik; AI661537; C8orf36; E3 SUMO-protein ligase NSE2; E3 SUMO-protein transferase NSE2; FLJ32440; hMMS21; methyl methanesulfonate sensitivity gene 21; MMS21; MMS21 homolog; non-SMC element 2 homolog; non-SMC element 2 homolog (MMS21, S. cerevisiae); non-SMC element 2, MMS21 homolog; non-SMC element 2, MMS21 homolog (S. cerevisiae); non-structural maintenance of chromosomes element 2 homolog; NSE2; NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase; NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase; NSMCE2; RGD1305156; Unknown (protein for MGC:133996); zinc finger, MIZ-type containing 7; ZMIZ7 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 286053 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.3 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q96MF7 | |
| Nsmce2 | |
| Recombinant Human NSMCE2. Recombinant protein control fragment (Product #RP-104928). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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