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Invitrogen™ Noggin Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA522795
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Beskrivelse
Suggested positive control: antigen standard for NOG (transient overexpression lysate).
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
Tekniske data
| Noggin | |
| Polyclonal | |
| Unconjugated | |
| NOG | |
| NOG; Noggin; Noggin precursor; noggin; LOW QUALITY PROTEIN: noggin; SYM1; symphalangism 1 (proximal); SYNS1; SYNS1A | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 18121, 25495, 9241 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| P97466, Q13253, Q62809 | |
| NOG | |
| Synthetic peptide comprising an internal sequence of the human Noggin protein. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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Produkttitel
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