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Niraparib tosylate, MedChemExpress

Artikelnummer. 16485046
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16485046 100 mg
16480427 50 mg
16446777 5 mg
16424078 10 mg
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Artikelnummer. 16485046 Leverandør Medchem Express Leverandørnr. HY10619B

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Beskrivelse

MedChemExpress Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively. Niraparib tosylate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively. Niraparib tosylate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Tekniske data

Kemisk navn eller materiale Niraparib tosylate
CAS 1038915-73-9
Farve White
Renhedsgrad noter Research
Molekylær formel C26H28N4O4S
Mængde 100 mg
Synonym MK-4827 tosylate
Opløselighedsinformation DMSO : 100 mg/mL (203.01 mM; ultrasonic and warming and heat to 60°C) ∣H2O : 1 mg/mL (2.03 mM; heat to 50°C)
SMIL NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O.O=S(C5=CC=C(C)C=C5)(O)=O
Molekylvægt (g/mol) 492.59
Formel vægt 492.59
Procent renhed 95.0%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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