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Niraparib, MedChemExpress

Artikelnummer. 16465046
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Artikelnummer. 16465046 Leverandør Medchem Express Leverandørnr. HY10619

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MedChemExpress Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Tekniske data

Kemisk navn eller materiale Niraparib
CAS 1038915-60-4
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C19H20N4O
Mængde 100 mg
Synonym MK-4827
Opløselighedsinformation DMSO : 25 mg/mL (78.03 mM; Need ultrasonic)
SMIL NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O
Molekylvægt (g/mol) 320.39
Formel vægt 320.39
Procent renhed 98.13%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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