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Niraparib hydrochloride, MedChemExpress

Artikelnummer. 16475046
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Artikelnummer. 16475046 Leverandør Medchem Express Leverandørnr. HY10619A

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MedChemExpress Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Tekniske data

Kemisk navn eller materiale Niraparib hydrochloride
CAS 1038915-64-8
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Renhedsgrad noter Research
Molekylær formel C19H21ClN4O
Mængde 100 mg
Synonym MK-4827 hydrochloride
Opløselighedsinformation DMSO : 250 mg/mL (700.57 mM; Need ultrasonic) ∣H2O : 100 mg/mL (280.23 mM; Need ultrasonic)
SMIL NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O.Cl
Molekylvægt (g/mol) 356.85
Formel vægt 356.85
Procent renhed 99.76%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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