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Nifedipine, 98%

Artikelnummer. 15495109
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Artikelnummer. 15495109 Leverandør Thermo Scientific Alfa Aesar Leverandørnr. J62811.06
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Description

L-type calcium channel blocker; induces apoptosis in human glioblastoma cells | CAS: 21829-25-4 | C17H18N2O6 | 346.34 g/mol

L-type calcium channel blocker; induces apoptosis in human glioblastoma cells.Nifedipine is a dihydropyridine calcium channel blocker used as L-type calcium channel blocker, antianginal and an antihypertensive . It induces apoptosis in human glioblastoma cells. It is used as a coronary vasodilator in the treatment of cardiac and circulatory disorders. Further, it is used in high-altitude medicine to treat high altitude pulmonary edema, hypertension and chronic stable angina. In addition, it is frequently used as a tocolytic agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
L-type calcium channel blocker; induces apoptosis in human glioblastoma cells.Nifedipine is a dihydropyridine calcium channel blocker used as L-type calcium channel blocker, antianginal and an antihypertensive . It induces apoptosis in human glioblastoma cells. It is used as a coronary vasodilator in the treatment of cardiac and circulatory disorders. Further, it is used in high-altitude medicine to treat high altitude pulmonary edema, hypertension and chronic stable angina. In addition, it is frequently used as a tocolytic agent.

Solubility
Soluble in acetone, methylene chloride, chloroform, ethyl acetate, dimethyl sulfoxide and methanol. Sparingly soluble in ethanol. Insoluble in water.

Notes
Light sensitive. Store in a cool place. Incompatible with strong acids, strong oxidizing agents, caustics, aliphatic amines, amides, diethylamine, potassium hydride and potassium hydroxide.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 21829-25-4
Molekylær formel C17H18N2O6
Molekylvægt (g/mol) 346.34
MDL nummer MFCD00057326
InChI nøgle HYIMSNHJOBLJNT-UHFFFAOYSA-N
Synonym nifedipine, procardia, adalat, procardia xl, adalat cc, cordipin, corinfar, fenihidine, citilat, oxcord
PubChem CID 4485
ChEBI CHEBI:7565
IUPAC navn 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
SMIL COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC

Specifications

Kemisk navn eller materiale Nifedipine
Smeltepunkt 171°C to 175°C
Farve White to Yellow
Mængde 5 g
Merck Index 14,6528
Opløselighedsinformation Soluble in acetone,methylene chloride,chloroform,ethyl acetate,dimethyl sulfoxide and methanol. Sparingly soluble in ethanol. Insoluble in water.
Formel vægt 346.33
Procent renhed 98%
Fysisk form Powder

Safety and Handling

compliance-icons
Product Identifier
  • Nifedipine
 Signal Word
  • Advarsel
 Hazard Category
  • Akut toksicitet Kategori 4
 Hazard Statement
  • H302-Farlig ved indtagelse.
 Precautionary Statement
  • P301+P312-I TILFÆLDE AF INDTAGELSE: I tilfælde af ubehag ring til en GIFTINFORMATIO / læge /
Supplemental information
  • MIXTURE LIST-Contain: Nifedipine

RUO – Research Use Only

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