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Nicotinamide, MedChemExpress

Artikelnummer. 16492059
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5 g
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16492059 1 g
16480788 5 g
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Artikelnummer. 16492059 Leverandør Medchem Express Leverandørnr. HYB0150
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Forventet forsendelse: 02-11-2026
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Description

MedChemExpress Nicotinamide is a form of vitamin B3 or niacin that inhibits sirtuin 2 (SIRT2) activity in vitro, with an EC50 of 2 μM. Nicotinamide inhibits up to 90% melanoma cell number and increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibts tumor growth in vivo and improves survival of melanoma-bearing mice, which can be used for the research of skin cancers such as melanoma.

Nicotinamide is a form of vitamin B3 or niacin that inhibits sirtuin 2 (SIRT2) activity in vitro, with an EC50 of 2 μM. Nicotinamide inhibits up to 90% melanoma cell number and increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibts tumor growth in vivo and improves survival of melanoma-bearing mice, which can be used for the research of skin cancers such as melanoma.

Specifications

Kemisk navn eller materiale Nicotinamide
CAS 98-92-0
Farve White
Renhedsgrad noter Research
Molekylær formel C6H6N2O
Mængde 1 g
Synonym Niacinamide Nicotinic acid amide
Opløselighedsinformation DMSO : 50 mg/mL (409.43 mM; Need ultrasonic) ∣H2O : ≥ 50 mg/mL (409.43 mM)
SMIL O=C(C1=CC=CN=C1)N
Molekylvægt (g/mol) 122.12
Formel vægt 122.12
Procent renhed 95.0%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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