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NG 52, MedChemExpress

Artikelnummer. 16486328
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5mg
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Artikelnummer. 16486328 Leverandør Medchem Express Leverandørnr. HY15154

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Beskrivelse

MedChemExpress NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 μM and 2 μM, respectively. NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2.5 μM. NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p.

NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 μM and 2 μM, respectively. NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2.5 μM. NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p.

Tekniske data

Kemisk navn eller materiale NG 52
CAS 212779-48-1
Farve White
Renhedsgrad noter Research
Molekylær formel C16H19ClN6O
Mængde 10 mg
Synonym Compound 52
Opløselighedsinformation DMSO : 100 mg/mL (288.34 mM; Need ultrasonic)
SMIL ClC1=CC(NC2=NC(NCCO)=NC3=C2N=CN3C(C)C)=CC=C1
Molekylvægt (g/mol) 346.81
Formel vægt 346.81
Procent renhed 99.91%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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