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Tocris Bioscience™ NFAT inhibitor, Cell Permeable
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Artikelnummer. 18706509
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Mængde:
1 mg
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18706509 1 mg
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Artikelnummer. 18706509 Leverandør Tocris Bioscience™ Leverandørnr. 5710/1

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Beskrivelse

Cell permeable NFAT inhibitor

NFAT inhibitor, Cell Permeable is an NFAT inhibitor. Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. Reduces inflammation and epithelial damage in a mouse model of colitis. In an animal model of Alzheimer's disease NFAT inhibitor improves cognitive and synaptic function, reduces glial activation and lowers amyloid levels; in vitro it reduces glutamate dysregulation and neuron hyperactivity.
TRUSTED_SUSTAINABILITY

Tekniske data

CAS 592517-80-1
Indhold og opbevaring Store at -20°C
Oversigt Protein Ser/Thr Phosphatase Inhibitors
Molekylvægt (g/mol) Observed M.W.: 3573.15
Mængde 1 mg
Strukturel form C147H259N67O36S
Produkttitel
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