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Tocris Bioscience™ Napabucasin
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Product Code. 18786549
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18786549 50 mg
18773249 10 mg
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Product Code. 18786549 Supplier Tocris Bioscience™ Supplier No. 5522/50

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Description

STAT3 inhibitor; also blocks cancer stem cell self-renewal

Napabucasin is a STAT3 inhibitor. Blocks spherogenesis of cancer stem cells (CSC), but not hematopoietic stem cells. Inhibits PaCa-2 xenograft tumor growth in mice, even after cessation of treatment, and decreases population of CSCs in PaCa-2 tumors from treated mice. Also blocks spleen and liver metastases of colon cancer cells in a mouse model.
TRUSTED_SUSTAINABILITY

Specifications

Kemisk navn eller materiale 2-Acetylnaphtho[2,3-b]furan-4,9-dione
CAS 83280-65-3
Mængde 50 mg
Mål STAT Inhibitors
Molekylær formel C14H8O4
Formel vægt 240.21
Renhed >98%
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