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N-Boc-trans-4-hydroxy-L-proline methyl ester, 97%, Thermo Scientific Chemicals

Catalog Number 15495198
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Quantity:
1 g
5 g
This item is not returnable. View return policy
74844-91-0
C11H19NO5
245.28
MFCD00076981
MZMNEDXVUJLQAF-SFYZADRCSA-N
boc-hyp-ome, n-boc-trans-4-hydroxy-l-proline methyl ester, 2s,4r-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate, 1-tert-butyl 2-methyl 2s,4r-4-hydroxypyrrolidine-1,2-dicarboxylate, boc-l-hydroxyproline methyl ester, boc-hydroxyproline-ome, methyl trans-1-boc-4-hydroxy-l-prolinate, n-tert-butoxycarbonyl-trans-4-hydroxy-l-proline methyl ester, trans-1-tert-butoxycarbonyl-4-hydroxy-l-proline methyl ester, n-boc-trans-4-hydroxyl-l-proline methyl ester
2734883
COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C
This item is not returnable. View return policy
74844-91-0
C11H19NO5
245.28
MFCD00076981
MZMNEDXVUJLQAF-SFYZADRCSA-N
boc-hyp-ome, n-boc-trans-4-hydroxy-l-proline methyl ester, 2s,4r-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate, 1-tert-butyl 2-methyl 2s,4r-4-hydroxypyrrolidine-1,2-dicarboxylate, boc-l-hydroxyproline methyl ester, boc-hydroxyproline-ome, methyl trans-1-boc-4-hydroxy-l-prolinate, n-tert-butoxycarbonyl-trans-4-hydroxy-l-proline methyl ester, trans-1-tert-butoxycarbonyl-4-hydroxy-l-proline methyl ester, n-boc-trans-4-hydroxyl-l-proline methyl ester
2734883
COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C

It is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.

Solubility
Soluble in chloroform, dichloromethane and ethyl acetate.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
TRUSTED_SUSTAINABILITY
Melting Point 92°C to 96°C
Quantity 5 g
Solubility Information Soluble in chloroform,dichloromethane and ethyl acetate.
Optical Rotation −65° (c=1 in Chloroform)
IUPAC Name 1-O-tert-butyl 2-O-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
Formula Weight 245.28
Percent Purity 97%
Chemical Name or Material N-Boc-trans-4-hydroxy-L-proline methyl ester

RUO – Research Use Only

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