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MYC tag Mouse anti-Tag, Clone: 1A5A2, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 60003-2-IG-150UL
Additional Details : Weight : 0.00010kg
Description
The antibody recognizes the Myc-tag EQKLISEEDL fused to either the amino- or carboxy- terminus of targeted proteins.
Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.Specifications
MYC tag | |
Monoclonal | |
0.85 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Mouse | |
Protein A | |
RUO | |
-20°C | |
Liquid | |
Tag |
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot | |
1A5A2 | |
Unconjugated | |
EQKLISEEDL, Myc tag | |
Peptide | |
150 μL | |
Primary | |
Antibody | |
IgG1 |