missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Proteinanalysereagenser
  4. Bioaktive små molekyler
  5. 30279884

Tocris Bioscience™ MS 4322

Artikelnummer. 30279884
Skift visning
Klik for at se tilgængelige muligheder
2 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Artikelnummer.
30279884 2 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Denne vare kan ikke returneres. Se returpolicy
Artikelnummer. 30279884 Leverandør Tocris Bioscience™ Leverandørnr. 8080/2

Please to purchase this item. Need a web account? Register with us today!

Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

Selective PRMT5 Degrader (PROTAC™)

MS 4322 is a protein arginine methyltransferase 5 (PRMT5) Degrader (PROTAC™) (DC50 = 1.1 μM, Dmax = 74% in MCF-7 cells). Also inhibits PRMT5 methyltransferase activity (IC50 = 18 nM) and dose-dependently inhibits proliferation of HeLa, A549, A172 and Jurkat cancer cell lines. Comprises a PRMT5 inhibitor linked to an E3 ligase ligand.

PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.

TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale N-((S)-3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-((1-((S)-19-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidine-1-carbonyl)-20,20-dimethyl-17-oxo-3,6,9,12,15-pentaoxa-18-azahenicosanoyl)azetidin-3-yl)amin
CAS 2375432-47-4
Mængde 2 mg
Mål Active Degraders
Molekylær formel C55H76N10O12S
Renhed 98%
Produkttitel
Vælg et problem

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.