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Tocris Bioscience™ Mpro 13b-K
Beskrivelse
Mpro 13b-K is a coronavirus Mpro inhibitor (IC50 values are 0.12, 0.58 and 0.9 μM for recombinant Mpro from SARS-CoV-2, MERS-CoV and SARS-CoV, respectively). Mpro 13b-K inhibits SARS-CoV-2 infection of human Calu3 cells (IC50 = 2.4 μM). The compound also inhibits SARS-CoV-2 replication in A549-ACE2-TMPRSS2, VeroE6 and Huh7 cell cultures (EC50 values are 0.84, 1.3 and 3.4 μM). Exhibits oral and inhalative bioavailability. Please note that this product was previously known as Mpro 13b.
Tekniske data
Tekniske data
| Kemisk navn eller materiale | tert-Butyl (1-((S)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate |
| CAS | 2412965-59-2 |
| Mængde | 5 mg |
| Mål | 3C and 3CL Protease Inhibitors |
| Molekylær formel | C31H39N5O7 |
| Renhed | 97% |
Produkttitel
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