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Invitrogen™ Mouse RIP3 Synthetic Peptide

Artikelnummer. 15216309
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Mængde:
50 μg
Pakningsstørrelse:
50µg
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15216309 50 μg 50µg
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Artikelnummer. 15216309 Leverandør Invitrogen™ Leverandørnr. PEP0081

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Beskrivelse

Synthetic Peptide

This peptide corresponds to 14 amino acids of mouse RIP3. PEP-0081 can be used as a blocking peptide with polyclonal antibody PA5-19956.

RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, which contains a C-terminal domain unique from other RIP family members. RIPK3 is predominantly localized to the cytoplasm, and specifically, are colocalized in the mitochondrion which can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. RIPK3 is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor and caspase-8 prevents RIPK3-dependent necrosis without inducing apoptosis by functioning in a proteolytically active complex with CFLAR and that this complex is required for the protective function.
TRUSTED_SUSTAINABILITY

Tekniske data

Gen-id (Entrez) 56532
Arter Mouse
Oprensningsmetode purified
Adgangsnummer Q9QZL0
Fælles navn RIP3
Koncentration 200 μg/mL
Indhold og opbevaring -20°C
Oversigt Synthetic Peptide
Format Liquid
Formulering PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Til brug med (applikation) Blocking Assay, Control
Gene Alias 2610528K09Rik; AW107945; Hcyp2; Homocysteine respondent protein HCYP2; mRIP3; receptor interacting protein 3; receptor interacting serine/threonine kinase 3; receptor-interacting protein 3; receptor-interacting serine/threonine-protein kinase 3; receptor-interacting serine-threonine kinase 3; Rip3; RIP-3; Ripk3; RIP-like protein kinase 3
Gen symbol RIPK3
Lyofiliseret, frysetørret No
Konserveringsmiddel Sodium azide
Produkttype Peptide
Mængde 50 μg
Regulatorisk status RUO
Opbevaringsbuffer PBS
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